Laboratory Test Information Guide

Details for Angiotensin Converting Enzyme, Serum

Test Name: Angiotensin Converting Enzyme, Serum
Alternate Name(s): ACE
Laboratory: Core
Specimen Type: Adult:
5 mL Gold top Vacutainer tube

0-2 years: 0.5 mL Red or Gold top Microtainer
2-10 years: 3 mL Red top Vacutainer tube
Collection Information: Collect after overnight fast to avoid interference from lipemia.

Minimum volume of serum required is 500 µL.
Test Schedule: Referred out Tuesday-Thursday
Turnaround time from when specimen
is received in testing laboratory:
7 days
Reference Range: <1 year: 16-126 U/L
1-3 years: 14-108 U/L
3-5 years: 12-89 U/L
5-10 years: 14-106 U/L
10-13 years: 15-111 U/L
13-17 years: 13-100 U/L
17-20 years: 11-79 U/L
>20 years: 9-63 U/L
Effective Date: 2017-11-07
Revised Date:  
Critical Value:  
Interpretive Comments: ACE is useful in the diagnosis and management of sarcoidosis. Elevated ACE activity is also reported in patients with Gaucher’s disease and Pneumyocystis carinii pneumonia. The test is also useful in monitoring the effect of ACE-inhibiting drugs. However, drugs targeting the renin-angiotensin system confound interpretation of ACE in relation to sarcoidosis.

Please note: Testing method changed November 7, 2017.
Special Processing:  
Method of Analysis: Enzymatic
Critical Information Required:  
Storage & Shipment: Store and ship serum frozen.
System Codes: 
Referred To: In-Common Laboratories

Questions? Comments? Contact Laura Gopaul