Laboratory Test Information Guide

Details for Cystatin C, Serum

Test Name: Cystatin C, Serum
Alternate Name(s):  
Laboratory: Core
Specimen Type: 5 mL Gold top Vacutainer tube

Pediatric:
0-2 years: 0.5 mL Red or Gold top Microtainer
2-10 years: 3 mL Red top Vacutainer tube
Collection Information: Minimum volume of serum required is 1 mL for adult samples or 0.5 mL for pediatric samples.

Separate and refrigerated or freeze.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: As requested
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
7 days
Stat
N/A
 
Reference Range: 0.61 - 0.95 mg/L
Glomerular Filtration Rate estimated from measured Cystatin C:
>90 mL/min
Effective Date: 2007-03-08
Revised Date: 2018-05-28
Critical Value:  
Interpretive Comments: CYSC eGFR calculation (Filler G, Lepage N, 2003)
eGFR: < 15 mL/min/1.73 m2
Consistent with kidney failure

eGFR: 15-29 mL/min/1.73 m2
Consistent with severe chronic kidney disease

eGFR: 30-44 mL/min/1.73 m2
Moderate to severe decreased kidney function is consistent with chronic kidney disease if confirmed over 3 months

eGFR: 45-59 mL/min/1.73 m2
Mild to moderate decreased kidney function is consistent with chronic kidney disease if confirmed over 3 months.

eGFR: 60-89 mL/min/1.73 m2
Consistent with mildly decreased kidney function, however, in the absence of other evidence of kidney disease, eGFR values in this range do not fulfill the KDIGO criteria for chronic kidney disease.
Interpret results in concert with ACR measurement.

eGFR: ≥ 90 mL/min/1.73 m2
Normal eGFR
Special Processing:  
Comments: CYSC eGFR is calculated based on the equation published by Filler G and Lepage N, Pediatr Nephrol 18: 981-985, 2003
Method of Analysis: Particle-enhanced turbidimetric immunoassay (PETIA) for the quantitative determination of Cystatin C in human serum
Critical Information Required:  
Storage & Shipment: Store and send refrigerated or frozen.

System Codes: 
Cerner
CYSC
 
Referred To:  

Questions? Comments? Contact Laura Gopaul