Laboratory Test Information Guide

Details for Free Prostate Specific Antigen, Plasma/Serum

Test Name: Free Prostate Specific Antigen, Plasma/Serum
Alternate Name(s): fPSA
PSA F
Free PSA
Laboratory: Core
Specimen Type: Adult:
4.5 mL Light Green top (Li-Heparin) Vacutainer tube

Red, Gold, or Lavender (EDTA) top tubes are also acceptable
Collection Information: Minimum volume of plasma or serum required is 700 L for adult samples samples.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
4 hours
Stat
N/A
 
Reference Range: Free PSA (g/L): no reference range available

Free PSA ratio: The probability of prostate cancer (PC) is inversely related to the ratio. Exact cut-offs appear to vary with patient age, the presence of benign prostate hypertrophy, and the analytical method (Laboratory Practice Guidelines of the Ontario Society of Clinical Chemists, October 2002).
Effective Date: 2018-03-06
Revised Date: 2018-08-17
Critical Value:  
Interpretive Comments: If the total PSA result is in the range of 4 10 g/L, a free PSA result could be of value in estimating the risk of prostate cancer in a patient with no previous diagnosis.
Special Processing:  
Comments: Biotin may interfere with this test. Samples should not be taken from patients receiving high biotin doses (i.e. > 5 mg/day) until at least 8 hours after the last biotin administration.
Method of Analysis: Roche Electrochemiluminescence
Critical Information Required:  
Storage & Shipment:  
System Codes: 
Cerner
PSAF
 
Referred To:  

Questions? Comments? Contact Laura Gopaul