Laboratory Test Information Guide

Details for IgG subclasses

Test Name: IgG subclasses
Alternate Name(s): IgG subtypes
IgG subsets
IgG1
IgG2
IgG3
IgG4
Laboratory: Clinical Immunology
Specimen Type: 6 mL Red top or 5 mL Gold top Vacutainer tube
Lithium heparinized plasma may also be accepted
Pediatric:
0 2 yrs: Red 1.0 pk
2 10 yrs: Red 2.0 mL
Collection Information: 1 mL serum required
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule:  
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
5 days
Stat
N/A
 
Reference Range: Subclass IgG1 g/L:

0-<2 years: 1.94-8.42
2-<4 years: 3.15-9.45
4-<6 years: 3.06-9.45
6-<8 years: 2.88-9.18
8-<10 years: 4.32-10.20
10-<12 years: 4.23-10.60
12-<14 years: 3.42-11.50
14-<18 years: 3.15-8.55
≥18 years: 3.82-9.29

Subclass IgG2 g/L:

0-<2 years: 0.23-3.00
2-<4 years: 0.36-2.25
4-<6 years: 0.61-3.45
6-<8 years: 0.44-3.75
8-<10 years: 0.72-4.30
10-<12 years: 0.76-3.55
12-<14 years: 1.00-4.55
14-<18 years: 0.64-4.95
≥18 years: 2.42-7.00

Subclass IgG3 g/L:

0-<2 years: 0.19-0.85
2-<4 years: 0.17-0.68
4-<6 years: 0.10-1.22
6-<8 years: 0.16-0.85
8-<10 years: 0.13-0.85
10-<12 years: 0.17-1.73
12-<14 years: 0.28-1.25
14-<18 years: 0.23-1.96
≥18 years: 0.22-1.76

Subclass IgG4 g/L:

0-<2 years: 0.005-0.784
2-<4 years: 0.010-0.537
4-<6 years: 0.018-1.125
6-<8 years: 0.004-0.992
8-<10 years: 0.019-0.932
10-<12 years: 0.016-1.150
12-<14 years: 0.037-1.360
14-<18 years: 0.110-1.570
≥18 years: 0.039-0.864
Effective Date: 2009-05-13
Revised Date: 2017-03-02
Critical Value:  
Interpretive Comments:  
Special Processing: Blood samples should be collected by venipuncture, allowed to clot naturally and the serum separated as soon as possible to prevent hemolysis.

Available for order in Powerchart by LHSC and SJHC physicians only.
Comments: IgG subclass testing includes IgG1, IgG2, IgG3 and IgG4 as reported values.
Method of Analysis: Turbidimetry
Critical Information Required: Patient's date of birth required.
Storage & Shipment: Since samples are batched preferred shipping and storage is at -20C. Samples may be held up to 8 days at 2C to 8C
System Codes: 
Cerner
IGGSUB
 
Referred To:  

Questions? Comments? Contact Laura Gopaul