Laboratory Test Information Guide

Details for Multiple Endocrine Neoplasia: Type 1

Test Name: Multiple Endocrine Neoplasia: Type 1
Alternate Name(s): MEN 1
Laboratory: Molecular Diagnostics
Specimen Type: Whole blood-2 x 4 mL Lavender EDTA top Vacutainer tube
Collection Information: Blood samples must be maintained at room temperature.
Test Schedule: As Required
Monday - Friday
0800 - 1600 h
Turnaround time from when specimen
is received in testing laboratory:
3 months
Reference Range: See report
Effective Date:  
Revised Date: 2016-03-21
Critical Value: N/A
Interpretive Comments: Multiple endocrine neoplasia type 1 (MEN 1) is a familial cancer syndrome characterized by parathyroid hyperplasia, pituiatary adenomas, and neuroendocrine tumors of the pancreas and duodenum. In 1997, the MEN1 tumor suppressor gene was identified, and numerous germline mutations have been reported distributed throughout the gene. These mutations include missense, nonsense, and frameshift mutations as well as mutations potentially responsible for abnormal RNA splicing, and highlight the need to investigate the entire MEN1 gene when characterizing new MEN 1 families.
Special Processing:  
Comments: For more information click on:
Molecular Diagnostic Laboratory
Method of Analysis: Mutation Scanning confirmed with DNA Sequence Analysis
Critical Information Required: Pedigree required.
Storage & Shipment: Must be received within 5 days of collection, shipped at room temperature by courier/overnight delivery.
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul