Laboratory Test Information Guide

Details for Primidone

Test Name: Primidone
Alternate Name(s): Anticonvulsant
Mysoline
Laboratory: Core
Specimen Type: 5 mL Gold top Vacutainer tube
Collection Information: Collect blood aseptically in a Vacutainer tube.

Minimum volume of required is 1 mL.

Spin and aliquot serum or plasma and freeze immediately and send to the lab.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: Referred out Monday - Thursday
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
2 days
Stat
N/A
 
Reference Range: 23.0-55.0 µmol/L

To monitor therapy draw trough specimens before the next dose is administered. The active metabolite Phenobarbital should be measured simultaneously.
Effective Date: 2009-03-10
Revised Date:  
Critical Value: Toxic:>68 µmol/L
CRITICAL VALUE to be phoned to Nurse/ Physician immediately
Interpretive Comments: A primidone level should only be considered in combination with the corresponding phenobarbital level, and more attention should be given to the phenobarbital level when a clinical decision is being made.
Special Processing:  
Comments: Referred out Monday - Thursday

Primidone is an anticonvulsant drug. Because primidone is partially metabolized to phenobarbital which has anticonvulsant activity itself, phenobarbital should be measured concurrently.
Method of Analysis:  
Critical Information Required:  
Storage & Shipment: Separate and freeze.
Ship on ice packs or frozen.
System Codes: 
Cerner
PRIM
 
Referred To: Hospitals In-Common Laboratory Inc.

Questions? Comments? Contact Laura Gopaul