Laboratory Test Information Guide

Details for Theophylline, Serum

Test Name: Theophylline, Serum
Alternate Name(s): Aminophylline
Theo-Dur
Somophyllin
Elixophyllin
Xanthine
Laboratory: Core
Specimen Type: Adult:
6 mL Red top Vacutainer tube

Pediatric:
0-2 years: 2 x 0.5 mL Red top Microtainers
2-10 years: 3 mL Red top Vacutainer tube

Blood collection tubes with separator gels are not recommended for this test.
Collection Information: Minimum volume of serum required is 0.5 mL.

Draw specimens at trough concentration prior to next regular dose.
Peak concentration is obtained 2 hours post oral dose.
Steady state is achieved during continuous IV therapy.
In premature infants and some neonates, the active metabolite caffeine may require simultaneous monitoring.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: Referred out Monday – Thursday
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
3 days
Stat
N/A
 
Reference Range: 55 - 110 µmol/L
Effective Date: 2010-08-31
Revised Date: 2019-06-04
Critical Value: Toxic: >110 µmol/L
Critical Value to be phoned to nurse or physician immediately
Interpretive Comments:  
Special Processing:  
Comments: Bronchodilator drug used in treatment of reversible bronchoconstriction.
Aminophylline is a salt of theophylline (80-85% by weight of this salt is theophylline).
Method of Analysis:  
Critical Information Required:  
Storage & Shipment: Store and ship serum frozen.
System Codes: 
Cerner
THEO
 
Referred To: In-Common Laboratories

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