Laboratory Test Information Guide

Details for Theophylline, Serum

Test Name: Theophylline, Serum
Alternate Name(s): Aminophylline
Theo-Dur
Somophyllin
Elixophyllin
Xanthine
Laboratory: Core
Specimen Type: 5 mL Gold top Vacutainer tube

Pediatric:
0-2 yrs: Red 0.5pk.
2-10 yrs: 2 mL Red top
Collection Information: Minimum volume of serum required is 0.5 mL.

Draw specimens at trough concentration prior to next regular dose. At peak concentration 2 h post oral dose or at steady state during continuous I.V. therapy. In premature infants and some neonates the active metabolite caffeine may require simultaneous monitoring.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
3 days
Stat
 
 
Reference Range: Bronchodilation: 55 - 110 µmol/L
Premature Apnea: 33 - 70 µmol/L
Toxic: Greater than 110 µmol/L
Effective Date: 2010-08-31
Revised Date:  
Critical Value: Critical Value to be phoned to nurse or physician immediately: Theophylline >110 µmol/L
Interpretive Comments:  
Special Processing:  
Comments: Referred out Tuesday - Thursday

Bronchodilator drug used in treatment of reversible broncho-constriction. Aminophylline is a salt of theophylline (80-85% by weight of this salt is theophylline).
Method of Analysis:  
Critical Information Required:  
Storage & Shipment:  
System Codes: 
Cerner
THEO
 
Referred To: Hospitals In-Common Laboratory Inc.

Questions? Comments? Contact Laura Gopaul