Laboratory Test Information Guide

Details for Thyroid Stimulating Hormone, Plasma/Serum

Test Name: Thyroid Stimulating Hormone, Plasma/Serum
Alternate Name(s): TSH
TSH-3
Thyrotropin
Laboratory: Core
Specimen Type: Adult:4.5 mL Green top Vacutainer tube

Pediatric:
0-2 years: 0.5 mL Light Green top (Li-Heparin) Microtainer
2-10 years: 3 mL Light Green top (Li-Heparin) Vacutainer tube

Red, Gold, or Lavender (EDTA) top tubes are also acceptable
Collection Information: Minimum volume of plasma or serum required is 700 L for adult samples or 200 L for pediatric samples.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
4 hours
Stat
1 hour
 
Reference Range: 0 6 days: 0.70 15.2 mIU/L
6 days 3 months: 0.72 11.0 mIU/L
3 12 months: 0.73 8.35 mIU/L
1 6 years: 0.70 5.97 mIU/L
6 11 years: 0.60 4.84 mIU/L
11 20 years: 0.51 4.30 mIU/L
> 20 years: 0.27 4.20 mIU/L
Effective Date: 2008-11-15
Revised Date: 2018-03-06
Critical Value:  
Interpretive Comments:  
Special Processing:  
Comments: TSH should be the initial test to screen for clinically-suspected hypothyroidism or hyperthyroidism. If TSH is below the lower cut-off, FT4 and FT3 testing will be performed reflexively by the laboratory. If TSH is between the lower and upper cut-offs, no FT4 or FT3 testing will be performed reflexively. If TSH is above the upper cut-off, FT4 testing will be performed reflexively by the laboratory. These cut-offs are the TSH reference intervals in children and the optimal cut-offs to predict abnormal FT4 levels in adults.

The TSH cut-offs are:
2 <6 years: <0.70 or >5.97 mIU/L
6 <11 years: <0.60 or >4.84 mIU/L
11 <18 years: <0.51 or >4.30 mIU/L
≥18 years: <0.58 or >6.30 mIU/L

Repeat testing of TSH should be limited to a period greater than 6 weeks, except in pregnant patients.

Biotin may interfere with this test. Samples should not be taken from patients receiving high biotin doses (i.e. > 5 mg/day) until at least 8 hours after the last biotin administration.
Method of Analysis: Roche Electrochemiluminescence
Critical Information Required:  
Storage & Shipment:  
System Codes: 
Cerner
TSH
 
Referred To:  

Questions? Comments? Contact Laura Gopaul