Laboratory Test Information Guide

Details for Anti Glomerular Basement Membrane, Serum

Test Name: Anti Glomerular Basement Membrane, Serum
Alternate Name(s): Anti GBM
Glomerular Basement Membrane, IgG antibody
Laboratory: Clinical Immunology
Specimen Type: 5 mL Gold top Vacutainer tube or 6 mL Red top Vacutainer tube. EDTA, heparin or citrated plasma are also acceptable.

0-2 years: Red 0.5 pk.
2-10 years: 2 mL Red top
Collection Information: Minimum volume of serum required is 0.5 mL.
Test Schedule: Routine: Wednesdays and Fridays

For STAT samples:
Availability of STAT testing is 0700-1500 hrs, seven days a week. ** Sample must be in Immunology by noon to insure testing is completed by 15:00** STAT testing must be pre-arranged with the Immunology Lab by calling ext. 35541. See "Critical Information Required" section prior to calling.
Turnaround time from when specimen
is received in testing laboratory:
3 days
See “ Test schedule” section
Reference Range: Negative: ≤19 RU/mL
Effective Date: 2010-01-11
Revised Date: 2020-05-20
Critical Value:  
Interpretive Comments: For the detection of IgG class antibodies to NC1 domain of Type 4 collagen found in glomerular basement membrane. Increases may occur in Goodpasture's Syndrome.
Special Processing:  
Comments: A single autoantibody test is not diagnostic and should not be used to determine course of treatment. The test result must be evaluated with consideration of clinical presentation, patient history and other laboratory tests.
Method of Analysis: Euroimmun Analyzer I-ELISA
Critical Information Required: For STAT testing of GBM, a diagnosis for Microscopic polyangiitis, Granulomatosis with polyangiitis (Wegener's granulomatosis), or Goodpasture's syndrome must be provided for testing to commence.
Storage & Shipment: Intercampus – Ship via routine or stat specimen transport. Serum can be stored for up to 4 days at 2 – 8oC. For longer storage, store at -20oC.

Intercity – Freeze and store serum samples at –20oC . Ship on ice packs. Avoid freeze/thaw cycles.
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul