Laboratory Test Information Guide

Details for Anti Glutamic Acid Decarboxylase, Serum/CSF

Test Name: Anti Glutamic Acid Decarboxylase, Serum/CSF
Alternate Name(s): AGAD
Anti-GAD65
Anti GAD
Glutamic Acid Decarboxylase-65 Antibodies
Laboratory: Clinical Immunology
Specimen Type: Adult:
5 mL Gold top Vacutainer tube or 6 mL Red top Vacutainer tube

Pediatric:
0-2 years: 0.5 mL Red top Microtainer
2-10 years: 2 mL Red top Vacutainer tube

CSF collected in a standard CSF tube.
Collection Information: Preferred volume of serum is 1 mL
Minimum volume of serum is 0.5 mL

Plasma is unacceptable

Lipemic or hemolytic serum samples are unacceptable.

CSF samples will also be accepted.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: Batch analysis
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
7 days
Stat
N/A
 
Reference Range: <5.0 IU/mL
Effective Date: 2010-06-01
Revised Date: 2021-05-19
Critical Value:  
Interpretive Comments: GAD65 antibodies are associated with systemic autoimmune diseases, including type 1 diabetes mellitus, thyroiditis and pernicious anemia. At high levels, they may be associated with neurological autoimmunity.
Special Processing:  
Comments:  
Method of Analysis: ELISA
Critical Information Required:  
Storage & Shipment: Send at room temperature.
Freezing and thawing may lead to a loss of activity

Stability
Room Temperature: 7 days
Refrigerated: 28 days
Frozen: 28 days
System Codes: 
Cerner
AGAD for Serum/AGADCSF for CSF
 
Referred To:  

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