Laboratory Test Information Guide

Details for BRAF NGS

Test Name: BRAF NGS
Alternate Name(s):  
Laboratory: Molecular Diagnostics
Specimen Type: FFPE
Collection Information: Send blocks to pathology lab for cutting
Requisition: Refer to Pathology
Test Schedule: Monday to Friday 0800-1600h
Turnaround time from when specimen
is received in testing laboratory:
15 days
Reference Range: See report
Effective Date:  
Revised Date:  
Critical Value: N/A
Interpretive Comments: In patients with advanced malignant melanoma BRAF V600 mutations have been shown to be associated with clinical response to therapies targeting BRAF, such as vemurafenib.(PMID: 2235632) While clinical guidelines for BRAF mutational analysis are evolving, current available guidelines recommend routine testing for BRAF V600 mutations in metastatic melanoma.(PMID:24129426)
Special Processing:  
Comments: Patient must meet CCO criteria for funding of test.
Method of Analysis: Mutation screening was performed by next generation sequencing (NGS) on the Ion Torrent technology using the Ion PGM™ System (ThermoFisher).
Critical Information Required:  
Storage & Shipment: Deliver to lab at room temperature.
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul