Laboratory Test Information Guide

Details for CA125, Plasma/Serum

Test Name: CA125, Plasma/Serum
Alternate Name(s):  
Laboratory: Core
Specimen Type: Adult:
4.5 mL Light Green top (Li-Heparin) Vacutainer tube

0-2 years: 0.5 mL Light Green top (Li-Heparin) Microtainer
2-10 years: 3 mL Light Green top (Li-Heparin) Vacutainer tube

Red, Gold, or Lavender (EDTA) top tubes are also acceptable
Collection Information: Minimum volume of plasma or serum required is 700 ÁL for adult samples or 200 ÁL for pediatric samples.
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
4 hours
Reference Range: ≤ 35 U/mL
Effective Date: 2018-03-06
Revised Date: 2018-08-17
Critical Value:  
Interpretive Comments: Elevations in serum CA125 occur in patients with ovarian carcinoma or adenocarcinoma of the endometrium or fallopian tubes. A rising value may be associated with progression of the disease. CA125 may also increase in pregnancy, breast carcinoma, liver cell carcinoma, bronchial carcinoma, benign ovarian tumours, peritoneal carcinoma, and liver cirrhosis. Mild increases also in renal failure.
Not recommended for cancer screening in asymptomatic women.
Special Processing:  
Comments: Biotin may interfere with this test. Samples should not be taken from patients receiving high biotin doses (i.e. > 5 mg/day) until at least 8 hours after the last biotin administration.
Method of Analysis: Roche Electrochemiluminescence
Critical Information Required:  
Storage & Shipment:  
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul