Laboratory Test Information Guide

Details for Chorionic Villi Sampling (CVS)

Test Name: Chorionic Villi Sampling (CVS)
Alternate Name(s): Chromosome Analysis
QF-PCR
Prenatal Microarray
Laboratory: Cytogenetics (VH)
Specimen Type: ~10-20 mg chorionic villi in a sterile container with RPMI media for QF-PCR, Microarray (if required) and back-up culture (additional sample required for external testing)

3ml EDTA Maternal Blood Sample
Collection Information: Patients should be referred to the Genetics Clinic at LHSC, VH (Ext.58140).
Must arrange in advance with Cytogenetics Lab (519-685-8500 Ext.78974 or Ext.75714).
Do not refrigerate, freeze or expose to heat.

System Codes:
CGen Pntl
QF-PCR (MD QF-PCR)
Microarray (MD Microarray
Requisition: CYTOGENETICS REQUISITION . (must include patient's name, address, Ontario Health Insurance Number, PIN (if applicable), originating location, Dr's full name and address, test requested, specimen type and pertinent clinical information.

PRENATAL MICROARRAY REQUISITION
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
QFPCR 3 days
Microarray or Chromosome Analysis - 2-3 weeks
Stat
 
 
Reference Range: See final report
Effective Date:  
Revised Date: 2017-03-24
Critical Value: See final report
Interpretive Comments: Prenatal diagnostic test performed at ~9-12 weeks gestation
Special Processing: Must prearrange with Cytogenetics Lab.
Comments: Contact the Cytogenetics Lab for aliquots of RPMI medium.

The Cytogenetics Lab is staffed from 0700-1700 (Monday-Friday), Ext. 78974 (office), or 75714 (lab).

For additional information please refer to the Cytogenetics Webpage.
Method of Analysis:  QF-PCR (Rapid Aneuploidy Detection)
Cell Culture
Chromosome Karyotyping (depending on QF-PCR results)
Prenatal Microarray (depending on clinical indications)
Fluorescence in situ hybridization (FISH) (depending on microarray results)
Critical Information Required:  
Storage & Shipment: If unable to transport immediately, store at 4oC and transport at room temperature (15-25oC) within 24 hours.
System Codes: 
Cerner
See Collection Information
 
Referred To:  

Questions? Comments? Contact Laura Gopaul