Laboratory Test Information Guide

Details for Chorionic Villi Sampling (CVS)

Test Name: Chorionic Villi Sampling (CVS)
Alternate Name(s): Chromosome Analysis
Prenatal Microarray
Laboratory: Cytogenetics (VH)
Specimen Type: ~10-20 mg chorionic villi in a sterile container with RPMI media for QF-PCR, Microarray (if required) and back-up culture (additional sample required for external testing)

3ml EDTA Maternal Blood Sample
Collection Information: Patients should be referred to the Genetics Clinic at LHSC, VH (Ext.58140).
Must arrange in advance with Cytogenetics Lab (519-685-8500 Ext.78974 or Ext.75714).
Do not refrigerate, freeze or expose to heat.

System Codes:
CGen Pntl
Microarray (MD Microarray
Requisition: CYTOGENETICS REQUISITION . (must include patient's name, address, Ontario Health Insurance Number, PIN (if applicable), originating location, Dr's full name and address, test requested, specimen type and pertinent clinical information.

Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
QFPCR 3 days
Microarray or Chromosome Analysis - 2-3 weeks
Reference Range: See final report
Effective Date:  
Revised Date: 2017-03-24
Critical Value: See final report
Interpretive Comments: Prenatal diagnostic test performed at ~9-12 weeks gestation
Special Processing: Must prearrange with Cytogenetics Lab.
Comments: Contact the Cytogenetics Lab for aliquots of RPMI medium.

The Cytogenetics Lab is staffed from 0700-1700 (Monday-Friday), Ext. 78974 (office), or 75714 (lab).

For additional information please refer to the Cytogenetics Webpage.
Method of Analysis:  QF-PCR (Rapid Aneuploidy Detection)
Cell Culture
Chromosome Karyotyping (depending on QF-PCR results)
Prenatal Microarray (depending on clinical indications)
Fluorescence in situ hybridization (FISH) (depending on microarray results)
Critical Information Required:  
Storage & Shipment: If unable to transport immediately, store at 4oC and transport at room temperature (15-25oC) within 24 hours.
System Codes: 
See Collection Information
Referred To:  

Questions? Comments? Contact Laura Gopaul