Laboratory Test Information Guide

Details for Clomipramine and Desmethylclomipramine, Serum/Plasma

Test Name: Clomipramine and Desmethylclomipramine, Serum/Plasma
Alternate Name(s): Desmethylclomipramine (metabolite)
Anafranil
Laboratory: Core
Specimen Type: 2 x 6 mL Red top Vacutainer or 2 x 4 mL Lavender top EDTA Vacutainer tube
Collection Information: Minimum volume required for testing is 3 mL

Separate as soon as possible
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
7 days
Stat
 
 
Reference Range: No reference range for Clomipramine OR Desmethylclomipramine alone.

Combined Metabolites

Clomipramine + Desmethylclomipramine
Adult Therapeutic Ranges:


580-1500 nmol/L

Toxic: >2000 nmol/L
Effective Date: 2005-07-01
Revised Date: 2016-08-27
Critical Value:  
Interpretive Comments:  
Special Processing: To monitor therapy, draw trough level specimen in TBEP-free tubes prior to morning dose or 10 - 12 h after last drug administration. Separate as soon as possible. Assay includes Desmethylclomipramine.
Comments: Referred out Tuesday - Thursday

Testing is also possible on urine and Gastric lavage samples.
Method of Analysis:  
Critical Information Required:  
Storage & Shipment:  
System Codes: 
Cerner
CLOM
 
Referred To: In-Common Laboratories

Questions? Comments? Contact Laura Gopaul