Antibodies against | Associated Neurological Disorders | Frequently Associated Tumors |
NMDAR | Anti-NMDAR encephalitis | Ovarian teratoma, testicular teratoma |
LGI1 | Limbic encephalitis | Thyroid carcinoma, small cell lung cancer, kidney cell carcinoma,
ovarian teratoma, thymoma
|
CASPR2 | Neuromyotonia, Morvan’s syndrome, Limbic encephalitis | Thymoma |
AMPAR1/R2 | Limbic encephalitis | Bronchial carcinoma, breast carcinoma, thymoma |
GABAB1/B2 | Limbic encephalitis | Small cell lung cancer |
DPPX | Anti-DPPX associated autoimmune
encephalitis
| |
Hu (ANNA-1) | Paraneoplastic encephalomyelitis | Small cell lung cancer, neuroblastoma |
Yo (PCA-1) | Paraneoplastic cerebellar degeneration | Ovarian cancer, breast cancer, uterine
carcinoma
|
Ri (ANNA-2) | Paraneoplastic opsoclonus myoclonus ataxia | Neuroblastoma, Breast cancer |
Ma2/Ta | Rhombencephalitis, paraneoplastic limbic encephalitis, brain stem encephalopathy | Germinal carcinoma of the
testis (seminoma)
|
Amphiphysin | Stiff-person syndrome, Myasthenic syndrome | Breast cancer, small cell lung cancer |
CV2 (CRMP5) | Limbic encephalitis | Small cell lung cancer, thymoma |
Recoverin | Retinopathy | Small cell lung cancer |
SOX1 | Lambert-Eaton myasthenic syndrome | Small cell lung cancer |
Titin | Myasthenia gravis | Thymoma |
Anti-Zic4 | Paraneoplastic cerebellar degeneration | Small cell lung cancer |
Tr (DNER) | Paraneoplastic cerebellar degeneration | Hodgkin‘s lymphoma |
GAD65 | Stiff-person syndrome | Small cell lung cancer |