Laboratory Test Information Guide

Details for Creutzfeldt-Jakob Disease (CJD) Protein Assay

Test Name: Creutzfeldt-Jakob Disease (CJD) Protein Assay
Alternate Name(s): CJD
Creutzfeldt-Jakob Disease
Laboratory: Microbiology (VH)
Specimen Type: Cerebrospinal Fluid
Collection Information: Before investigation can proceed:

- Neurology and IPAC must be notified of the case
- All CSF tubes collected, regardless of intended laboratory investigation(s), must be labeled with ‘Suspect CJD’ sticker
- A Dedicated CSF tube for CJD testing must be collected
- The CSF tube for CJD must be accompanied by a completed requisition

Submit 2-3 mL of CSF in a sterile, plastic container. (Minimum 1.0 mL)

Samples with visible blood or xanthochromia are unsuitable.

Post mortem samples will not be processed

Cerner Orderable: CJDRO – Restricted to Neurology and Neurosurgical services
Requisition: REQUISITION FOR TESTING
Test Schedule: Referred out Monday, Tuesday and Wednesday to the National Microbiology Laboratory in Winnipeg.
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
15 days
Stat
 
 
Reference Range:  
Effective Date: 2006-07-01
Revised Date: 2018-11-23
Critical Value:  
Interpretive Comments:  
Special Processing:  
Comments: Please notify Microbiology (VH) before submitting sample.
Method of Analysis: Quaking Induced Conversion Assay (EP-QuIC)
Protein ELISA (14-3-3 and Tau)
Critical Information Required: A fully completed requisition must accompany the sample for referral, with complete clinical history.
Storage & Shipment: The specimen must be shipped to the Microbiology Lab, as soon as possible.
System Codes: 
Cerner
CJDRO – Restricted to Neuro.
 
Referred To: Attention: D. Godal/T.D. Airey
Host Genetics and Prion Diseases
National Microbiology Laboratory, Health Canada
1015 Arlington Street
Winnipeg, Manitoba
R3E 3R2

Phone: 204-789-6078 - for up-to-date protocol
Fax: 204-789-5009

Questions? Comments? Contact Laura Gopaul