Laboratory Test Information Guide

Details for Digoxin

Test Name: Digoxin
Alternate Name(s): Lanoxin
Laboratory: Core UH & VH
Specimen Type: 4.5 mL Green (Lithium Heparin) top Vacutainer tube

Plasma from a 5 mL Gold top or 6 mL Red top Vacutainer tube is also acceptable.

0-2 years: 0.5 mL Green Microtainer
2-10 years: 2 mL Green top tube
Collection Information: Collect blood aseptically in a Vacutainer tube.
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
3 hours
1 hour
Reference Range: Therapeutic range: 1.0 to 2.6 nmol/L

Congestive heart failure: 0.6 to 1.0 nmol/L
Effective Date: 2008-11-15
Revised Date: 2021-06-23
Critical Value: Toxic:
>3.0 nmol/L
Interpretive Comments: Therapeutic digoxin concentrations vary significantly, depending upon the individual. The lower limit for one patient may be ineffective in another, while the upper limit may prove toxic in a third. The physician should determine the appropriate reference interval for each patient.
Special Processing:  
Comments: CRITICAL VALUE to be phoned to Nurse or Physician immediately:
Method of Analysis: Enzyme immunoassay (EIA)
Critical Information Required:  
Storage & Shipment: Serum/Plasma must be separated from the cells within 2 hours of collection. Store at 15-30 degrees Celsius for no longer than 8 hours. Specimen can be stored at 2-8 degrees Celsius for up to 48 hours. If analysis has not been started before 48 hours then the specimen must be frozen.
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul