Laboratory Test Information Guide

Details for HLA Antibody BM/SC Recipient Workup

Test Name: HLA Antibody BM/SC Recipient Workup
Alternate Name(s): BoneMarrow/StemCell Recipient Antibody Workup
Laboratory: Transplant
Specimen Type: 1 x 6mL Red top Vacutainer tube-No additives or separator gel. (2mL to 6 mL for paeds)
Collection Information: BM/SC transplant workups are coordinated by the Bone Marrow Transplant Coordinator who can be contacted via the LHSC switchboard (519-658-8500)

Testing is only performed for patients involved in the London Transplant Program. Unrelated marrow / stem cell donors are not normally tested in this laboratory. Please contact the laboratory (519-663-3320) if other situations apply to your patient
Test Schedule: As required Monday to Friday except Stat holidays
Turnaround time from when specimen
is received in testing laboratory:
1-3 days
Reference Range: cPRA 0-100%
Effective Date: 2020-08-24
Revised Date:  
Critical Value:  
Interpretive Comments: Anti-HLA antibodies indicate potential sensitization to potential donors and some blood products.
Special Processing:  
Method of Analysis: cPRA determinations are determined with the CBS cPRA calculator and are based on specificities detected with solid phase bead technology using the Luminex® platform.
Critical Information Required: DSA analysis requires knowledge of the HLA typing of the donor or prospective donor of interest. Patients who were not transplanted in the London program will need to have this information forwarded to this laboratory.
Storage & Shipment: Samples drawn at LHSC are delivered to the Transplant Laboratory at room temperature.

Samples for Antibody Testing (1 red top) drawn outside of LHSC must be spun and the serum removed and frozen. Ship on dry ice if shipping requires >24 hours. Ship frozen on freezer packs if the sample will be received in < 24 hours.
System Codes: 
HLA BMSC Antibody Recipient
Referred To:  

Questions? Comments? Contact Laura Gopaul