Laboratory Test Information Guide

Details for HLA Disease Association

Test Name: HLA Disease Association
Alternate Name(s): HLA Pharmacogenomics
Laboratory: Transplant
Specimen Type: 2 x 4 mL Lavender (EDTA) top Vacutainer tubes

Note: Increase collection volumes if leukocyte count is low, smaller volumes apply for paediatric patients.

Paediatric Patients:
<1 year: 2 mL EDTA
1-10 years: 2 mL EDTA
10-18 years: 4 mL EDTA

Contact the laboratory if these volumes are not possible: 519-663-3320
Collection Information: Samples that are being shipped into the laboratory can be drawn Monday- Friday.
Test Schedule: Monday to Friday
Turnaround time from when specimen
is received in testing laboratory:
14 days
Reference Range: See report
Effective Date: 2020-06-29
Revised Date:  
Critical Value:  
Interpretive Comments:  
Special Processing:  
Comments: You will be prompted to indicate the antigen and disease of interest when the “HLA Disease Association” order is selected.
Antigen/Allele of InterestDiseaseComments
B27Ankylosing SpondylitisOrder HLAB27 Test
DQ2/DQ8CeliacOrder HLA Celiac Investigation

Antigen/Allele of InterestDiseaseComments
B*57:01Abacavir Hypersensitivity
B*15:02Carbamazepine Hypersensitivity(Asians)
A*31:01Carbamazepine Hypersensitivity/SJS(Caucasians)
B*58:01Allopurinol Hypersensitivity/SJS

Please contact the laboratory 519-663-3320 if there are any questions.
Method of Analysis: HLA Class I and Class II typings are performed using molecular techniques (RSSO or SSP).
Critical Information Required: Must indicate the HLA antigen and the disease of interest when placing the order.
Storage & Shipment: Keep EDTA blood at room temperature and deliver within 72 hours.
System Codes: 
HLA Disease Association (DA)
Referred To:  

Questions? Comments? Contact Laura Gopaul