Laboratory Test Information Guide

Details for Hemoglobinopathy Screen

Test Name: Hemoglobinopathy Screen
Alternate Name(s): Hemoglobin F (Fetal)
Hemoglobin A2
Hemoglobin Electrophoresis
Hemoglobin H
Ferritin Level
Laboratory: Clinical Immunology
Specimen Type: Peripheral Blood

4 mL K2 or K3 EDTA Lavender top Vacutainer tube
5 mL Red top Vacutainer tube

0-2 years: Lavender 1.0 pk., Red 0.5 pk
2-10 years: 2 mL Lavender top, 2 mL Red top
Collection Information: Specimen should be transported at room temperature, stored at 2-8C prior to testing.

For referred-in (non-LHSC) samples:
1. Include the following:
Requisition with patient demographics (HCN included)
Available pertinent familial history or information:
ethnic origin, known affected family members
patient transfused before sample drawn
patient planning a pregnancy
CBC results
Stained blood film reflecting the CBC results
A fax number to which the report can be sent

2. Send to:
Sample Receiving Area
Room D1-206
London Health Sciences Centre
800 Commissioners Rd., London, ON
N6A 5W9

3. Notify laboratory (519-685-8300 ext. 33097 or 77676) prior to sending sample.
Test Schedule: Bi-weekly
Turnaround time from when specimen
is received in testing laboratory:
3 weeks
Sickle Cell patients having scheduled or unscheduled surgery. Weekdays. Call 33097 or 77676
Reference Range: Hb A:
Newborn-1 month: <=10.0
1-3 months: 21.1-56.6
3-6 months: 50.7-85.6
6-7 months: 83.5-96.8
>7 months: 95.5-97.6

Hb F:
Newborn-1 month: <=90.0
1-3 months: 42.4-75.6
3-6 months: 12.4-46.0
6-7 months: 1.2-13.2
>7 months: 0.0-1.2

Hb A2:

Hb H:
Effective Date: 2008-05-27
Revised Date: 2019-06-18
Critical Value:  
Interpretive Comments: Screening procedure includes CBC, serum Ferritin level, Hemoglobin Electrophoresis with quantitation of hemoglobin fractions, and when indicated, HbS Solubility test, or HbH Preparation.
Special Processing:  
Method of Analysis: Microscopy
Capillary Electrophoresis
Critical Information Required: Any clinical history or relevant patient history.
Storage & Shipment: Ship sample at room temperature.

Store specimen at 2-8 Celsius prior to testing.

Samples must be received for testing within 24 hours of collection.
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul