Laboratory Test Information Guide

Details for IgG Subclasses, Serum/Plasma

Test Name: IgG Subclasses, Serum/Plasma
Alternate Name(s): IgG subtypes
IgG subsets
IgG1
IgG2
IgG3
IgG4
Laboratory: Clinical Immunology
Specimen Type: Adult:
5 mL Gold top Vacutainer tube

Pediatric:
0-2 years: 0.5 mL Red or Gold top Microtainer
2-10 years: 3 mL Red top Vacutainer tube

Light Green (Li-Heparin) or Lavender (EDTA) top tubes are also acceptable
Collection Information: Minimum volume of serum required is 500 L for adult samples or 200 L for pediatric samples.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule: Monday Friday
0800-1600
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
5 days
Stat
N/A
 
Reference Range: Subclass IgG1 g/L:

0-<2 years: 1.94-8.42
2-<4 years: 3.15-9.45
4-<6 years: 3.06-9.45
6-<8 years: 2.88-9.18
8-<10 years: 4.32-10.20
10-<12 years: 4.23-10.60
12-<14 years: 3.42-11.50
14-<18 years: 3.15-8.55
≥18 years: 3.82-9.29

Subclass IgG2 g/L:

0-<2 years: 0.23-3.00
2-<4 years: 0.36-2.25
4-<6 years: 0.61-3.45
6-<8 years: 0.44-3.75
8-<10 years: 0.72-4.30
10-<12 years: 0.76-3.55
12-<14 years: 1.00-4.55
14-<18 years: 0.64-4.95
≥18 years: 2.42-7.00

Subclass IgG3 g/L:

0-<2 years: 0.19-0.85
2-<4 years: 0.17-0.68
4-<6 years: 0.10-1.22
6-<8 years: 0.16-0.85
8-<10 years: 0.13-0.85
10-<12 years: 0.17-1.73
12-<14 years: 0.28-1.25
14-<18 years: 0.23-1.96
≥18 years: 0.22-1.76

Subclass IgG4 g/L:

0-<2 years: 0.005-0.784
2-<4 years: 0.010-0.537
4-<6 years: 0.018-1.125
6-<8 years: 0.004-0.992
8-<10 years: 0.019-0.932
10-<12 years: 0.016-1.150
12-<14 years: 0.037-1.360
14-<18 years: 0.110-1.570
≥18 years: 0.039-0.864
Effective Date: 2009-05-13
Revised Date: 2020-05-25
Critical Value:  
Interpretive Comments:  
Special Processing:  
Comments: IgG subclass testing includes IgG1, IgG2, IgG3 and IgG4 as reported values.
Method of Analysis: Turbidimetry
Critical Information Required:  
Storage & Shipment: Store and ship serum or plasma refrigerated. Frozen serum or plasma is also acceptable.
System Codes: 
Cerner
IGGSUB
 
Referred To:  

Questions? Comments? Contact Laura Gopaul