Laboratory Test Information Guide

Details for Porphyrins, 24-Hour Urine

Test Name: Porphyrins, 24-Hour Urine
Alternate Name(s): Urine Porphyrins
24 hour Urine Porphyrin
Uroporphyrin I
Uroporphyrin III
Heptacarboxylic Acid
Hexacarbolic Acid
Pentacarboxylic Acid
Coproporphyrin I
Coproporphyrin III
Laboratory: Core
Specimen Type: 24 hour urine collected with 5g sodium carbonate. Containers with appropriate additives are obtained from the Core Laboratory.
Collection Information: Collection of 24-Hour Urine Sample

Keep specimen in dark and cool during collection.

Please complete the laboratory label attached to the collection bottle to include patientís name, collection start time and date and collection end time and date.
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
10 days
Reference Range: Note: Reference ranges are for adults only. Reference ranges not available for individuals 17 years of age and younger.

Uroporphyrin I: <= 44 nmol/d
Uroporphyrin III: <= 20 nmol/d
Heptacarboxylic Acid: 1-16 nmol/d
Hexacarbolic Acid: <= 2 nmol/d
Pentacarboxylic Acid: <= 2 nmol/d
Coproporphyrin I: 5-90 nmol/d
Coproporphyrin III: 15-242 nmol/d
Copro III/Copro I ratio: 2.6-5.3

Interpretation provided on report.
Effective Date: 2003-07-08
Revised Date: 2019-02-21
Critical Value:  
Interpretive Comments:  
Special Processing: Final pH should be 8 to 10. Collection not suitable for ALA/PBG testing. See "Porphyrin Precursors" for ALA/PBG testing.
Quantitation may only be done if preliminary screen is positive.
Method of Analysis: HPLC
Critical Information Required: Provide volume (in litres) and collection date.
Storage & Shipment: Keep the samples protected from light. Store and send frozen.
System Codes: 
Referred To: In-Common Laboratories

Questions? Comments? Contact Laura Gopaul