Laboratory Test Information Guide

Details for Protein,Urine

Test Name: Protein,Urine
Alternate Name(s):  
Laboratory: Core
Specimen Type: Random urine
Collection Information: Collect a minimum of 5 mL of random urine in a sterile container.
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
4 hours
1 hour
Reference Range: Reference range for urine protein:
0.0 0.15 g/L

Reference ranges for protein:creatinine ratio:
children and adults: <23 mg/mmol creatinine
pregnant women: <30 mg/mmol creatinine
Effective Date: 2008-11-15
Revised Date: 2017-09-16
Critical Value:  
Interpretive Comments: Useful in the evaluation of renal disease.
Screening for monoclonal gammopathy.
Increased amounts of protein in the urine may be due to:
(1) Glomerular proteinuria: caused by defects in the glomerular filtration barrier permeability (e.g. glomerulonephritis or nephrotic syndrome);
(2) Tubular proteinuria: inadequate tubular reabsorption of proteins (e.g. interstitial nephritis);
(3) Overflow proteinuria: caused by increased plasma concentration of protein(s) (e.g. multiple myeloma, myoglobinuria); and
(4) Urinary tract inflammation or tumour
Special Processing:  
Comments: Contamination of urine with menstrual blood, prostatic secretions, or semen may contribute to increased urine protein levels (false-positives).

When protein is ordered on a random urine, creatinine will be ordered automatically and the protein:creatinine ratio will calculate automatically.
Method of Analysis: Turbidimetric
Critical Information Required:  
Storage & Shipment:  
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul