Laboratory Test Information Guide

Details for Renin, Plasma

Test Name: Renin, Plasma
Alternate Name(s): Direct Renin
Renin Mass
Laboratory: Endocrinology
Specimen Type: Adult:
4 mL Lavender top (EDTA) Vacutainer tube

0-2 years: 2 x 0.5 mL Lavender top (EDTA) Microtainers
2-10 years: 3 mL Lavender top (EDTA) Vacutainer tube

Red, Gold, Light Green (Li-Heparin), or Lavender (EDTA) top tubes are NOT acceptable
Collection Information: Minimum volume of plasma required is 500 L.

Patient should be on a normal salt diet for at least 3 days prior to test.

Supine: Patient should be lying supine for at least 30 minutes prior to blood collection.

Standing: Blood should be collected midmorning (ideally), after the patient has been up (sitting, standing, or walking) for at least 2 hours and then seated for 5-15 minutes.

If test has been ordered without a requested posture, collect a standing sample.
Test Schedule: Monday-Friday
Turnaround time from when specimen
is received in testing laboratory:
5 days
Reference Range: Age 20 60 years:
supine: 1.7 23.9 ng/L
standing: 2.6 27.7 ng/L
Effective Date:  
Revised Date: 2020-05-25
Critical Value:  
Interpretive Comments: Plasma renin levels are very high at birth and gradually decline to adult levels after 1 year of age.
Special Processing: Sample should be spun in a centrifuge at room temperature. If possible, separate plasma into 2 aliquots of at least 500 L each and then freeze.
Method of Analysis: Diasorin Chemiluminescence
Critical Information Required:  
Storage & Shipment: Store and ship plasma frozen.
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul