Laboratory Test Information Guide

Details for Serum Free Light Chains

Test Name: Serum Free Light Chains
Alternate Name(s): Free Kappa light chains
Free Lambda light chains
Immunoglobulins, Free light chains
Laboratory: Clinical Immunology
Specimen Type: 5 mL Gold top Vacutainer tube
Collection Information: Minimum volume of serum required is 750 ÁL

Note: Serial FLC analysis should only be performed for patients with AL amyloidosis, light chain myeloma and non-secretory myeloma. Repeat collection frequency is limited to >=3 weeks. If a FLC is ordered and it has been <20 days since the last collection, the test will be cancelled.
Requisition: GENERAL LABORATORY REQUISITION
Test Schedule:  
Turnaround time from when specimen
is received in testing laboratory:
 
Routine
5 days
Stat
N/A
 
Reference Range: Free Kappa Chains: 3.3-19.4 mg/L
Free Lambda Chains: 5.7-26.3 mg/L
Kappa:Lambda ratio: 0.26-1.65
Effective Date: 2009-02-13
Revised Date: 2019-03-14
Critical Value:  
Interpretive Comments: A persistent and aberrant Kappa:Lambda ratio supports a diagnosis of monoclonal gammopathy.
Special Processing:  
Comments:  
Method of Analysis: Immunoturbidimetry
Critical Information Required:  
Storage & Shipment: Store and send refrigerated.
System Codes: 
Cerner
FLC
 
Referred To:  

Questions? Comments? Contact Laura Gopaul