| Test Name: | Thioridazine and Metabolite, Serum/Plasma |
| Alternate Name(s): | Mellaril® |
| Laboratory: | Core |
| Specimen Type: | 5 mL Gold top Vacutainer tube
Avoid gel-separator tubes |
| Collection Information: | Minimum volume required is 1 mL. |
| Requisition: | GENERAL LABORATORY REQUISITION |
| Test Schedule: | Referred out Monday-Thursday |
Turnaround time from when specimen
is received in testing laboratory: | | | |
| Reference Range: | Thioridazine steady-state serum concentration during chronic oral administration of 400 mg daily: 140 - 2600 ng/mL
Therapeutic steady-state concentrations may overlap levels associated with toxicity.
Mesoridazine therapeutic range: 100 - 1400 ng/mL |
| Effective Date: | |
| Revised Date: | 2020-06-22 |
| Critical Value: | Toxic: Greater than 27 µmol/L |
| Interpretive Comments: | See Phenothiazine Screen for Qualitative test on Urine sample. |
| Special Processing: | Test is also available on gastric lavage and random urine samples. |
| Comments: | Thioridazine is a phenothiazine for treating psychosis. Monitoring its level is important to optimize therapy, to avoid toxicity, and to assure compliance. |
| Method of Analysis: | Gas Chromatography |
| Critical Information Required: | |
| Storage & Shipment: | Store and send cold.
Specimen Stability:
Ambient: 8 days
Refrigerated: 8 days
Frozen: 1 year |
| System Codes: | | |
| Referred To: | Hospitals In-Common Laboratory Inc. |
