Laboratory Test Information Guide

Details for Tricyclic Screen

Test Name: Tricyclic Screen
Alternate Name(s): Tricyclics, Plasma
Laboratory: Core
Specimen Type: 4.5 mL Green (Lithium Heparin) top Vacutainer tube (preferred) or 5 mL Gold top Vacutainer tube

0-2 years: 0.5 mL Green Microtainer
2-10 years: 2 mL Green top tube
Collection Information: Collect blood aseptically in a Vacutainer tube.

Serum from a 5 mL Gold top or 6 mL Red top Vacutainer tube is also acceptable.
Test Schedule: As required
Turnaround time from when specimen
is received in testing laboratory:
24 hours
1 hour
Reference Range: Negative
Effective Date: 2009-06-04
Revised Date: 2012-01-27
Critical Value:  
Interpretive Comments: A positive result in this drug screen indicates that tricyclic antidepressants may be present in serum at a mimimum concentration of 300 mg/ml, and is to be regarded as preliminary/presumptive unless subsequently verified by a definitive confirmation test on a urine specimen that is collected simultaneously or within 24 hours of teh serum samples that tested positive (available upon request by calling the Toxicology Laboratory.)
Note that this screen is susceptible to false positive responses from other drugs such as diphenhydramine (eg: Gravol) and antihistamines, cyclobenzaprine and other muscle relaxants, phenothiazines and other antipsychotics, and carbamazepine.
Special Processing:  
Method of Analysis: EMIT immunoassay
Critical Information Required:  
Storage & Shipment:  
System Codes: 
Referred To:  

Questions? Comments? Contact Laura Gopaul